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For Healthcare ProfessionalsIntended for US Audiences

Personalized dosing, patient by patient

60potential fewer infusions per year while maintaining efficacy.1,4

Two dosing infusion options1

2

Standard Every-Second-Day Prophylaxis

ADVATE [Antihemophilic Factor (Recombinant)] offers personalized dosing, patient by patient with up to 60 potential fewer infusions per year while maintaining efficacy. Features two dosing options with either standard every-second-day prophylaxis and every-third day-prophylaxis.
Infusion Days
3

Every-Third-Day Prophylaxis

ADVATE [Antihemophilic Factor (Recombinant)] offers personalized dosing, patient by patient with up to 60 potential fewer infusions per year while maintaining efficacy. Features two dosing options with either standard every-second-day prophylaxis and every-third day-prophylaxis.

Your patients may be candidates for every-third-day dosing if:

  • Their treatment is on-demand and they have a bleed frequency of 4 to 6 times per month or more, and they want fewer bleeds with fewer scheduled infusions1
  • Their current prophylaxis treatment regimen is 3 times per week or more, and they want fewer scheduled infusions

If your patients ask about dosing less frequently, see if every-third-day dosing is right for them.

  • Patients must carefully follow your instructions regarding the dose and schedule for infusing ADVATE [Antihemophilic Factor (Recombinant)] so that their treatment will work best for them
  • Your patients must be willing to have blood tests to help determine their appropriate starting dose (as it may be higher than their current dose)1
BAXJECT III System: Only ADVATE offers the BAXJECT III system, an all-in-one reconstitution system available in 11 different potencies.
BAXJECT III System: Only ADVATE offers the BAXJECT III system, an all-in-one reconstitution system available in 11 different potencies.

Plus, personalize dosing with a broad selection of ADVATE vials1,3

  • 11 potencies, which provide more options for single-vial infusions–more than any other FVIII product
  • 7 different potencies available with 2 mL diluent volume, up to 1700 IU
  • 4 different potencies available with 5 mL diluent volume, from 2000 IU to 4000 IU

Find a single vial dose

Find your patient’s prescribed dose of ADVATE. Find
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500 IU

As of [variable date], Shire has [variable quantity] IU single-dose vials of ADVATE available in our inventory.

Based on your patient’s prescription, this is the closest single-vial dose opportunity currently available.

Based on your patient’s prescription, there is no ADVATE single vial dose opportunity available at this time.

Connect with a Shire Representative to find out how your patient’s factor provider can order the ADVATE prescription in a single vial.

The ADVATE Single Vial Dose Finder is designed to illustrate which single-vial dosing options for ADVATE are available at any time. Please note that the displayed vial is for demonstration purposes only and the actual vial will be provided from the closest dosing option available.